Hot Off the Press – December 22, 2022 Summary Neurons communicate via electrical signals – spikes – and recording these has provided fundamental information regarding how the brain works. When neurons send electrical signals, several other biological signals occur, notably calcium. Calcium signaling is often used to make inferences about spike activity. However, it was… [Read More]
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Kauê Costa named an Allen Institute Next Generation Leader
The Allen Institute has announced six new Next Generation Leaders (NGL), members of a unique neuroscience advisory panel made up of early-career researchers who will help advise research efforts at the Allen Institute for Brain Science, the MindScope Program, and the Allen Institute for Neural Dynamics. Among the new panel members is Kauê Machado Costa,… [Read More]
Technology Development Initiative – Paper of the Month – December 2022
Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery Published in Nature Nanotechnology. Authors Curtis Dobrowolski, Kalina Paunovska, Elisa Schrader Echeverri, David Loughrey, Alejandro J. Da Silva Sanchez, Huanzhen Ni, Marine Z. C. Hatit, Melissa P. Lokugamage, Yanina Kuzminich, Hannah E. Peck, Philip J. Santangelo & James E. Dahlman Paper… [Read More]
Muscarinic Acetylcholine M2 Receptors Regulate Lateral Habenula Neuron Activity and Control Cocaine Seeking Behavior
Featured Paper of the Month – December 2022 Published in The Journal of Neuroscience by Clara Wolfe and Carl Lupica et al. of the NIDA IRP Electrophysiology Research Section. Summary The lateral habenula (LHb) is a brain region receiving information from brain areas involved in decision making, with influence on motivation, reward, and movement. This… [Read More]
Incubation of palatable food craving is associated with brain-wide neuronal activation in mice
Hot Off the Press – November 21, 2022 Summary Relapse to reward seeking progressively increases during abstinence, a behavioral phenomenon termed incubation of craving. Mechanistic studies of incubation can lead to novel relapse treatments. However, previous studies have primarily used rat models and targeted region-by-region analyses, and a brain-wide functional atlas of incubation of reward… [Read More]
Yavin Shaham Wins the 2022 Ruth L. Kirschstein Mentoring Award
Yavin Shaham, Ph.D., Chief of Behavioral Neuroscience Research Branch and Neurobiology of Relapse Section has been awarded the 2022 Ruth L. Kirschstein mentoring award by the National Institutes of Health (NIH) as part of the 2022 NIH Director’s Awards. The NIH Director’s Awards recognizes exceptional performance and special efforts beyond regular job assignments. The Ruth… [Read More]
Technology Development Initiative – Paper of the Month – November 2022
Transgenic mice for in vivo epigenome editing with CRISPR-based systems Published in Nature Methods. Authors Matthew P. Gemberling, Keith Siklenka, Erica Rodriguez, Katherine R. Tonn-Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, Liqing Li, Valentina Cigliola, Mariah F. Hazlett, Courtney A. Williams, Luke C. Bartelt, Victoria J. Madigan, Josephine C. Bodle, Heather Daniels, Douglas C. Rouse,… [Read More]
Misconfigured striatal connectivity profiles in smokers
Featured Paper of the Month – November 2022 Published in Neuropsychopharmacology by Thomas Ross and Elliot Stein of the NIDA IRP Neuroimaging Research Branch. Summary The striatum, part of the forebrain, is critically involved in reward processes and substance use. Many of the inputs to the striatum come from frontal brain regions. One way to… [Read More]
John Hubbard awarded 2022 Humanitarian & Service PA of the Year Award
John Hubbard, MPAS, PA-C in the NIDA IRP OCD, has been awarded the 2022 Humanitarian & Service PA of the Year Award from the Maryland Academy of Physician Assistants. The MdAPA Humanitarian & Service Award seeks to recognize a PA who has shown incredible service to the community, providing care to the most vulnerable and… [Read More]
Technology Development Initiative – Paper of the Month – October 2022
Dense functional and molecular readout of a circuit hub in sensory cortex Published in Science. Authors Cameron Condylis, Abed Ghanbari, Nikita Manjrekar, Karina Bistrong, Shenqin Yao, Zizhen Yao, Thuc Nghi Nguyen, Hongkui Zeng, Bosiljka Tasic, and Jerry L. Chen Paper presented by Dr. Atul Daiwile and selected by the NIDA TDI Paper of the Month… [Read More]
