Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery Published in Nature Nanotechnology. Authors Curtis Dobrowolski, Kalina Paunovska, Elisa Schrader Echeverri, David Loughrey, Alejandro J. Da Silva Sanchez, Huanzhen Ni, Marine Z. C. Hatit, Melissa P. Lokugamage, Yanina Kuzminich, Hannah E. Peck, Philip J. Santangelo & James E. Dahlman Paper… [Read More]
Technology Development Initiative Paper of the Month
Technology Development Initiative – Paper of the Month – November 2022
Transgenic mice for in vivo epigenome editing with CRISPR-based systems Published in Nature Methods. Authors Matthew P. Gemberling, Keith Siklenka, Erica Rodriguez, Katherine R. Tonn-Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, Liqing Li, Valentina Cigliola, Mariah F. Hazlett, Courtney A. Williams, Luke C. Bartelt, Victoria J. Madigan, Josephine C. Bodle, Heather Daniels, Douglas C. Rouse,… [Read More]
Technology Development Initiative – Paper of the Month – October 2022
Dense functional and molecular readout of a circuit hub in sensory cortex Published in Science. Authors Cameron Condylis, Abed Ghanbari, Nikita Manjrekar, Karina Bistrong, Shenqin Yao, Zizhen Yao, Thuc Nghi Nguyen, Hongkui Zeng, Bosiljka Tasic, and Jerry L. Chen Paper presented by Dr. Atul Daiwile and selected by the NIDA TDI Paper of the Month… [Read More]
Technology Development Initiative – Paper of the Month – September 2022
SMART: An Open-Source Extension of WholeBrain for Intact Mouse Brain Registration and Segmentation Published in eNeuro. Authors Michelle Jin, Joseph D Nguyen, Sophia J Weber, Carlos A Mejias-Aponte, Rajtarun Madangopal, Sam A Golden Paper presented by Dr. Katherine Savell and selected by the NIDA TDI Paper of the Month Committee. Background and Technological Advancement Whole-brain… [Read More]
Technology Development Initiative – Paper of the Month – August 2022
An integrated wearable microneedle array for the continuous monitoring of multiple biomarkers in interstitial fluid Published in Nature Biomedical Engineering. Authors Farshad Tehrani, Hazhir Teymourian, Brian Wuerstle, Jonathan Kavner, Ravi Patel, Allison Furmidge, Reza Aghavali, Hamed Hosseini-Toudeshki, Christopher Brown, Fangyu Zhang, Kuldeep Mahato, Zhengxing Li, Abbas Barfidokht, Lu Yin, Paul Warren, Nickey Huang, Zina Patel,… [Read More]
Technology Development Initiative – Paper of the Month – July 2022
Verification of technical characteristics and performance of VeinViewer Flex, ICEN IN-G090-2 and AccuVein AV400 transillumination devices Published in Clinica Chimica Acta. Authors Adrijana Dorotić, Ivona Kuktić, Dora Vuljanić, Ana-Maria Šimundić Paper presented by Dr. Kathleen Trychta and selected by the NIDA TDI Paper of the Month Committee Publication Brief Description Background: Venous blood sampling and… [Read More]
Technology Development Initiative – Paper of the Month – June 2022
Enhancer viruses for combinatorial cell-subclass-specific labeling Published in Neuron. Authors: Lucas T Graybuck, Tanya L Daigle, Adriana E Sedeño-Cortés, Miranda Walker, Brian Kalmbach, Garreck H Lenz, Elyse Morin, Thuc Nghi Nguyen, Emma Garren, Jacqueline L Bendrick, Tae Kyung Kim, Thomas Zhou, Marty Mortrud, Shenqin Yao, La’ Akea Siverts, Rachael Larsen, Bryan B Gore, Eric R… [Read More]
Technology Development Initiative – Paper of the Month – May 2022
A chromatin integration labelling method enables epigenomic profiling with lower input Published in Nature Cell Biology. Authors: Akihito Harada, Kazumitsu Maehara, Tetsuya Handa, Yasuhiro Arimura, Jumpei Nogami, Yoko Hayashi-Takanaka, Katsuhiko Shirahige, Hitoshi Kurumizaka, Hiroshi Kimura, Yasuyuki Ohkawa Paper presented by Dr. Atul Daiwile and selected by the NIDA TDI Paper of the Month Committee Publication… [Read More]
Technology Development Initiative – Paper of the Month – April 2022
Closed-loop wearable naloxone injector system Published in Scientific Reports. Authors: Justin Chan, Vikram Iyer, Anran Wang, Alexander Lyness, Preetma Kooner, Jacob Sunshine & Shyamnath Gollakota Paper presented by Dr. Albert Burgess-Hull and selected by the NIDA TDI Paper of the Month Committee Summary Opioid overdose deaths in the US are the highest they have ever… [Read More]
