On Thursday, May 14, 2026, the NIDA IRP Clinical Program welcomed representatives from the Office of the Lieutenant Governor. Aruna Miller and her staff received a tour of our facilities and learned about the cutting edge research we are conducting in the field of addiction medicine.
Hot Off the Press
VTA monosynaptic connections by local glutamate and GABA neurons and their distinct roles in behavior
Hot Off the Press – January 2026 Published in Nature Communications by Flavia Barbano and Marisela Morales et al. of the NIDA IRP Neuronal Networks Section. Summary This study demonstrates that the ventral tegmental area (VTA), a brain region central to motivation and reward, contains tightly organized local circuits that shape behavior in distinct ways…. [Read More]
Reviews To Read
Morphinan Alkaloids and Their Transformations: A Historical Perspective of a Century of Opioid Research in Hungary
Reviews To Read – July 2025. Published in International Journal of Molecular Sciences with contributions by Kenner Rice of the NIDA IRP Drug Design and Synthesis Section. The word opium derives from the ancient Greek word ὄπιον (ópion) for the juice of any plant, but today means the air-dried seed capsule latex of Papaver somniferum. Alkaloid… [Read More]
Featured Papers
Brain CB2 receptor: a new target in medication development for treating opioid use disorder in rodents
Featured Paper of the Month – July 2026
Published in Molecular Psychiatry by Omar Soler-Cedeño and Zheng-Xiong Xi, et al. of the NIDA IRP Addiction Biology Unit.
This study tested a novel compound, MRI-2594, to determine whether it could reduce opioid use and relapse-related behaviors in rats and mice.
