Lorenzo Leggio, M.D., Ph.D. is a 2023 recipient of the Arthur S. Flemming Award for his exceptional service as a Federal Employee. Dr. Leggio received his award in a ceremony on November 14, 2024. The Flemming Awards are managed by the George Washington University’s Trachtenberg School of Public Policy and recipients include many notable figures… [Read More]
Hot Off the Press
Hippocampal output suppresses orbitofrontal cortex schema cell formation
Hot Off the Press – August 21, 2025 Published in Nature Neuroscience by Wenhui Zong and Geoffrey Schoenbaum, et al. of the NIDA IRP Behavioral Neurophysiology Neuroscience Section. Summary The orbitofrontal cortex (OFC) and hippocampus (HC) are both thought to contribute to the construction of cognitive maps and their generalization into schemas, yet the nature… [Read More]
Reviews To Read
Morphinan Alkaloids and Their Transformations: A Historical Perspective of a Century of Opioid Research in Hungary
Reviews To Read – July 2025. Published in International Journal of Molecular Sciences with contributions by Kenner Rice of the NIDA IRP Drug Design and Synthesis Section. The word opium derives from the ancient Greek word ὄπιον (ópion) for the juice of any plant, but today means the air-dried seed capsule latex of Papaver somniferum. Alkaloid… [Read More]
Featured Papers
Modification of Brain Connectome on Association Between Adverse Childhood Experiences and Development of Mental Disorders in Preadolescence
Featured Paper of the Month – April 2026
Published in JAMA Network Open by Xiang Xiao and Yihong Yang et al. of the NIDA IRP Magnetic Resonance Imaging and Spectroscopy Section.
In this study, we addressed the question of whether a brain marker moderates the association between childhood adversity and psychiatric disorders during the transition to adolescence.
