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National Institute on Drug Abuse - Intramural Research Program

  National Institute on Drug Abuse | NIH IRP | Treatment Information
  • Home
  • News
    • Featured Paper of the Month
    • Reviews to Read
    • Hot off the Press
    • IRP News
    • Awards
    • Technology Development Initiative Paper of the Month
    • Seminar Schedule
  • About
    • About NIDA IRP
    • Contact Us
    • Directions and Map
    • Careers at NIDA IRP
  • Organization
    • Faculty
    • Office of the Scientific Director
    • Office of the Clinical Director
    • Office of Education and Career Development
    • Administrative Management Branch
    • Molecular Targets and Medications Discovery Branch
    • Cellular and Neurocomputational Systems Branch
    • Molecular Neuropsychiatry Research Branch
    • Neuroimaging Research Branch
    • Behavioral Neuroscience Research Branch
    • Integrative Neuroscience Research Branch
    • Translational Addiction Medicine Branch
    • Core Facilities
    • Women Scientist Advisors
  • Training Programs
    • Office of Education and Career Development
    • OECD Awards
    • Summer Internship Program
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    • NIDA Speakers Bureau
    • Clinical Electives Program
  • Study Volunteers

Featured Paper of the Month

The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys

April 2016 Featured Papers Image - Small

Featured Paper of the Month – April 2016
Justinova, Zuzana; Panlilio, Leigh V; Secci, Maria E; Redhi, Godfrey H; Schindler, Charles W; Cross, Alan J; Mrzljak, Ladislav; Medd, Amy; Shaham, Yavin; Goldberg, Steven R
Biol Psychiatry, 78 (7), pp. 452–462, 2015, ISSN: 1873-2402 (Electronic); 0006-3223 (Linking).
[Read More]

Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model

March 2016 Featured Papers Image - Small

Featured Paper of the Month – March 2016
Caprioli, Daniele; Venniro, Marco; Zeric, Tamara; Li, Xuan; Adhikary, Sweta; Madangopal, Rajtarun; Marchant, Nathan J; Lucantonio, Federica; Schoenbaum, Geoffrey; Bossert, Jennifer M; Shaham, Yavin
Biol Psychiatry, 78 (7), pp. 463–473, 2015, ISSN: 1873-2402 (Electronic); 0006-3223 (Linking).
[Read More]

Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area

February 2016 Featured Paper Image - Small

Featured Paper of the Month – February 2016
Wang, Huikun; Treadway, Tyler; Covey, Daniel P; Cheer, Joseph F; Lupica, Carl R
Cell Rep, 12 (12), pp. 1997–2008, 2015, ISSN: 2211-1247 (Electronic).
[Read More]

High Affinity Dopamine D3 Receptor (D3R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D3R Knockout Mice

January 2016 Featured Paper Image - Small

Featured Paper of the Month – January 2016
Boateng, Comfort A; Bakare, Oluyomi M; Zhan, Jia; Banala, Ashwini K; Burzynski, Caitlin; Pommier, Elie; Keck, Thomas M; Donthamsetti, Prashant; Javitch, Jonathan A; Rais, Rana; Slusher, Barbara S; Xi, Zheng-Xiong; Newman, Amy Hauck
J Med Chem, 58 (15), pp. 6195–6213, 2015, ISSN: 1520-4804 (Electronic); 0022-2623 (Linking).
[Read More]

Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists.

December 2015 Featured Papers Image - Small

Featured Paper of the Month – December 2015
Selfridge, Brandon R; Wang, Xiaohui; Zhang, Yingning; Yin, Hang; Grace, Peter M; Watkins, Linda R; Jacobson, Arthur E; Rice, Kenner C
J Med Chem, 58 (12), pp. 5038–5052, 2015, ISSN: 1520-4804 (Electronic); 0022-2623 (Linking).
[Read More]

Impaired functional connectivity within and between frontostriatal circuits and its association with compulsive drug use and trait impulsivity in cocaine addiction.

November 2015 Featured Papers Image - Small

Featured Paper of the Month – November 2015
Hu, Yuzheng; Salmeron, Betty Jo; Gu, Hong; Stein, Elliot A; Yang, Yihong
JAMA Psychiatry, 72 (6), pp. 584–592, 2015, ISSN: 2168-6238 (Electronic); 2168-622X (Linking).
[Read More]

Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters.

October 2015 Featured Papers Image

Featured Paper of the Month – October 2015
Stolzenberg, Sebastian; Quick, Matthias; Zhao, Chunfeng; Gotfryd, Kamil; Khelashvili, George; Gether, Ulrik; Loland, Claus J; Javitch, Jonathan A; Noskov, Sergei; Weinstein, Harel; Shi, Lei
J Biol Chem, 290 (22), pp. 13992–14003, 2015, ISSN: 1083-351X (Electronic); 0021-9258 (Linking).
[Read More]

Incubation of methamphetamine craving is associated with selective increases in expression of Bdnf and Trkb, glutamate receptors, and epigenetic enzymes in cue-activated fos-expressing dorsal striatal neurons.

September 2015 Featured Paper Image

Featured Paper of the Month – September 2015
Li, Xuan; Rubio, Javier F; Zeric, Tamara; Bossert, Jennifer M; Kambhampati, Sarita; Cates, Hannah M; Kennedy, Pamela J; Liu, Qing-Rong; Cimbro, Raffaello; Hope, Bruce T; Nestler, Eric J; Shaham, Yavin
J Neurosci, 35 (21), pp. 8232–8244, 2015, ISSN: 1529-2401 (Electronic); 0270-6474 (Linking).
[Read More]

Norepinephrine activates dopamine D4 receptors in the rat lateral habenula.

August 2015 Featured Papers Image - Small

Featured Paper of the Month – August 2015
Root, David H; Hoffman, Alexander F; Good, Cameron H; Zhang, Shiliang; Gigante, Eduardo; Lupica, Carl R; Morales, Marisela
J Neurosci, 35 (8), pp. 3460–3469, 2015, ISSN: 1529-2401 (Electronic); 0270-6474 (Linking).
[Read More]

Basal Hippocampal Activity and Its Functional Connectivity Predicts Cocaine Relapse

July 2015 Featured Papers Image - Small

Featured Paper of the Month – July 2015
Adinoff, Bryon; Gu, Hong; Merrick, Carmen; McHugh, Meredith; Jeon-Slaughter, Haekyung; Lu, Hanzhang; Yang, Yihong; Stein, Elliot A
Biol Psychiatry, 78 (7), pp. 496–504, 2015, ISSN: 1873-2402 (Electronic); 0006-3223 (Linking).
[Read More]

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