Featured Paper of the Month – December 2022
Published in The Journal of Neuroscience by Clara Wolfe and Carl Lupica et al. of the NIDA IRP Electrophysiology Research Section.
The lateral habenula (LHb) is a brain region receiving information from brain areas involved in decision making, with influence on motivation, reward, and movement. This interface between thoughts, emotions, and actions is how the LHb permits adaptive behavior, and LHb dysfunction is implicated in psychiatric and drug use disorders. Silencing the LHb impairs control over cocaine seeking in rats and muscarinic acetylcholine receptors (mAChR) are also implicated…