A division of the Neuroimaging Research Branch
Investigators: Hanbing Lu, Ph.D., Yihong Yang, Ph.D., Elliot A. Stein, Ph.D.
Biomedical Research Center
251 Bayview Blvd
Suite 200, Room 07A711A
Baltimore, MD 21224
About the Lab
The Preclinical (Translational) Imaging Unit pursues the following objectives:
- To determine, at a systems level, the neurobiological consequences following acute and chronic administration of, and withdrawal from, psychostimulant drugs such as nicotine and cocaine in preclinical models of drug dependence.
- Applying several NHP models to understand the long term consequences of early developmental stress and chronic methamphetamine administration on brain structure, function and biochemistry.
- To develop and apply the use of manganese enhanced MRI (MEMI) to determine neuronal pathways mediating the acute and long term plastic effects of abused drugs.
- To develop novel structural, functional and biochemical techniques in preclinical models of drug dependence, including CBV, ASL, MRS, MEMRI.
- To develop and apply quantitative cerebral blood flow measures in preclinical models of stroke.