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NIDA IRP

National Institute on Drug Abuse - Intramural Research Program

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Preclinical (Translational) Imaging Unit

A division of the Neuroimaging Research Branch

Section Chief

Investigators: Hanbing Lu, Ph.D., Yihong Yang, Ph.D., Elliot A. Stein, Ph.D.

Contact

Location:
Biomedical Research Center
251 Bayview Blvd
Suite 200, Room 07A711A
Baltimore, MD 21224

Phone: 443-740-2650

Fax: 443-740-2753

Email: estein@mail.nih.gov

About the Lab

The Preclinical (Translational) Imaging Unit pursues the following objectives:

  • To determine, at a systems level, the neurobiological consequences following acute and chronic administration of, and withdrawal from, psychostimulant drugs such as nicotine and cocaine in preclinical models of drug dependence.
  • Applying several NHP models to understand the long term consequences of early developmental stress and chronic methamphetamine administration on brain structure, function and biochemistry.
  • To develop and apply the use of manganese enhanced MRI (MEMI) to determine neuronal pathways mediating the acute and long term plastic effects of abused drugs.
  • To develop novel structural, functional and biochemical techniques in preclinical models of drug dependence, including CBV, ASL, MRS, MEMRI.
  • To develop and apply quantitative cerebral blood flow measures in preclinical models of stroke.

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Preclinical (Translational) Imaging Unit

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Organization

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  • Behavioral Neuroscience Research Branch
  • Integrative Neuroscience Research Branch
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