A division of the Neuroimaging Research Branch
Section Chief
Investigators: Hanbing Lu, Ph.D., Yihong Yang, Ph.D., Elliot A. Stein, Ph.D.
Contact
Location:
Biomedical Research Center
251 Bayview Blvd
Suite 200, Room 07A711A
Baltimore, MD 21224
Phone: 443-740-2650
Fax: 443-740-2753
Email: estein@mail.nih.gov
About the Lab
The Preclinical (Translational) Imaging Unit pursues the following objectives:
- To determine, at a systems level, the neurobiological consequences following acute and chronic administration of, and withdrawal from, psychostimulant drugs such as nicotine and cocaine in preclinical models of drug dependence.
- Applying several NHP models to understand the long term consequences of early developmental stress and chronic methamphetamine administration on brain structure, function and biochemistry.
- To develop and apply the use of manganese enhanced MRI (MEMI) to determine neuronal pathways mediating the acute and long term plastic effects of abused drugs.
- To develop novel structural, functional and biochemical techniques in preclinical models of drug dependence, including CBV, ASL, MRS, MEMRI.
- To develop and apply quantitative cerebral blood flow measures in preclinical models of stroke.
