Reviews To Read – August 28, 2018. The increasing use of marijuana, its derivatives, and synthetic cannabinoids for medicinal and recreational purposes has increased interest in understanding the addictive potential of this class of molecules. Studies show that nearly 1 in 10 marijuana users will eventually show signs of dependence on the drug, which is… [Read More]
Reviews to Read
Context-induced relapse after extinction versus punishment: similarities and differences.
Reviews To Read – June 14, 2018. This review, which is part of a special issue of Psychopharmacology on “Extinction” summarizes recent research on similarities and differences in the neuronal mechanisms of context-induced relapse after extinction-imposed abstinence (the classical model) versus context-induced relapse after punishment-imposed abstinence (the new model).
Discovery and development of varenicline for smoking cessation
Reviews To Read – April 3, 2018. from the Addiction Biology Unit Quitting smoking is challenging. The recent development of varenicline (Chantix®) for smoking cessation is a successful story. In this article, we review the strong theoretical rationale, major findings in preclinical and clinical studies with varenicline, and post-market surveillance. We also discuss current major… [Read More]
Misuse of Novel Synthetic Opioids: A Deadly New Trend.
Reviews To Read – March 1, 2018. The United States is experiencing an epidemic of opioid overdose deaths. A major factor in this crisis is the increasing availability of potent opioid drugs, including fentanyl and novel synthetic opioids (NSOs). NSOs include various analogs of fentanyl and newly-emerging non-fentanyl compounds which stimulate mu-opioid receptor proteins in… [Read More]
Compulsive Seekers: Our take. Two Clinicians’ Perspective on a New Animal Model of Addiction
Reviews To Read – January 3, 2018. From the NIDA IRP Real World Assessment, Prediction and Treatment Unit. In this invited commentary, Bill Kowalczyk and I weighed in on a new rat model of addiction developed by Chiara Giuliano in Barry Everitt’s lab at the University of Cambridge. Like other recently developed models of addiction,… [Read More]
Preclinical Studies of Cannabinoid Reward, Treatments for Cannabis Use Disorder, and Addiction-Related Effects of Cannabinoid Exposure
Reviews To Read – November 20, 2017
Panlilio, Leigh V; Justinova, Zuzana
Neuropsychopharmacology. 2017 Aug 28.
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Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases.
Reviews To Read – September 2017
Weng, Tzu-Yu; Tsai, Shang-Yi Anne; Su, Tsung
J Biomed Sci, 24 (1), pp. 74, 2017, ISSN: 1423-0127 (Electronic); 1021-7770 (Linking).
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Ventral tegmental area: cellular heterogeneity, connectivity and behaviour.
Reviews To Read – June 2017
Morales, Marisela; Margolis, Elyssa B
Nat Rev Neurosci, 18 (2), pp. 73–85, 2017, ISSN: 1471-0048 (Electronic); 1471-003X (Linking).
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Computational approaches to detect allosteric pathways in transmembrane molecular machines.
Reviews To Read – May 2017
Stolzenberg, Sebastian; Michino, Mayako; LeVine, Michael V; Weinstein, Harel; Shi, Lei
Biochim Biophys Acta, 1858 (7 Pt B), pp. 1652-1662, 2016, ISSN: 0006-3002 (Print); 0006-3002 (Linking).
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The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems.
Reviews To Read – January 2017
Su, Tsung-Ping; Su, Tzu-Chieh; Nakamura, Yoki; Tsai, Shang-Yi
Trends Pharmacol Sci, 37 (4), pp. 262–278, 2016, ISSN: 1873-3735 (Electronic); 0165-6147 (Linking).
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