
Contact
Biomedical Research Center251 Bayview Blvd.
Suite 200
Room 08A505.18
Baltimore, MD 21224
Phone: 443-740-2730
Email: renata.marchette@nih.gov
Education
Ph.D. in Pharmacology - Universidade Federal de Santa Catarina, Florianopolis, SC, Brazil
M.Sc. in Pharmacology - Universidade Federal de Santa Catarina, Florianopolis, SC, Brazil
Pharm.D. - Universidade Estadual Paulista (UNESP), Araraquara, SP, Brazil
Research Interests
My long-term research interests are focused on the understanding of the neurobiological basis of psychiatric disorders and the pursuit of new treatments for these disorders. During my Ph.D. I systematically investigated the involvement of the HPA axis and the tachykinergic system in vulnerability and resilience to social defeat stress in mice. I joined the Koob Lab in 2018 and my research focuses on the involvement of brain stress systems and their sexual dimorphism in drug addiction. My goal is to identify new pharmacological targets for the understanding of drug addiction. I have systematically studied opioid seeking and taking behavior in a recently developed mouse model of opioid vapor self-administration in mice. Using modern techniques, I hope to uncover new druggable targets that are functionally linked to pathology and that can be modulated to facilitate recovery or confer resilience in mental disorders with a focus on addiction.
Selected Publications
Publications from the Neurobiology of Addiction Section.
2021
Operant Vapor Self-administration in Mice Journal Article
In: Bio Protoc, vol. 11, no. 10, pp. e4023, 2021, ISSN: 2331-8325.
κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats Journal Article
In: Neurobiol Stress, vol. 14, pp. 100325, 2021, ISSN: 2352-2895.
2020
Fentanyl vapor self-administration model in mice to study opioid addiction. Journal Article
In: Sci Adv, vol. 6, no. 32, pp. eabc0413, 2020.
