Description and Mission
The CBPC is a collaborative initiative between multiple laboratories across intramural institutes. The consortium facilitates investigating synaptic level neural mechanisms in nonhuman primates and drawing comparisons to the mechanism found in rodent brains. The consortium is also an effective platform for developing and testing viral techniques for use in nonhuman primates as it allows functional validation of virally delivered constructs in the slice. Translation of viral techniques from rodents to primates is challenging, but it is an important step towards development of next-generation therapeutics. Specific projects in the consortium include investigation of mechanisms of inhibition in neocortex and hippocampus, dopamine release in the striatum, axonal physiology of dopamine neurons within the striatum, and the contribution of basal forebrain cholinergic neurons to learning.
CBPC Contacts
Bruno Averbeck, Ph.D
Senior Investigator, NIMH
bruno.averbeck@nih.gov
Sebastian Peña-Vargas
Program Analyst, CCB
sebastian.penavargas@nih.gov
Members
Veronica Alvarez
Laboratory on Neurobiology of Compulsive Behaviors
NIMH
Bruno Averbeck
Section on Learning and Decision Making
NIMH
Zayd Khaliq
Cellular Neurophysiology Section
NIMH
Chris McBain
Section on Cellular and Synaptic Physiology
NICHD
Lorna Role/David Talmage
Circuits, Synapses, and Molecular Signaling Section
NINDS
