Hot Off the Press! – February 2015
Zhang, Shiliang; Qi, Jia; Li, Xueping; Wang, Hui-Ling; Britt, Jonathan P; Hoffman, Alexander F; Bonci, Antonello; Lupica, Carl R; Morales, Marisela
Nat Neurosci, 18 (3), pp. 386–392, 2015, ISSN: 1546-1726 (Electronic); 1097-6256 (Linking).
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Synthesis and immunological effects of heroin vaccines
Featured Paper of the Month – February 2015
Published in Organic Biomolecular Chemistry by Li, Fuying; Cheng, Kejun; Antoline, Joshua F G; Iyer, Malliga R; Matyas, Gary R; Torres, Oscar B; Jalah, Rashmi; Beck, Zoltan; Alving, Carl R; Parrish, Damon A; Deschamps, Jeffrey R; Jacobson, Arthur E; Rice, Kenner C
Three haptens have been synthesized with linkers for attachment to carrier macromolecules at either the piperidino-nitrogen or via an introduced 3-amino group. Two of the haptens, with a 2-oxopropyl functionality at either C6, or at both the C3 and C6 positions on the 4,5-epoxymorphinan framework, as well as the third hapten (DiAmHap) with diamido moieties at both the C3 and C6 positions, should be much more stable in solution, or in vivo in a vaccine, than a hapten with an ester in one of those positions, as found in many heroin-based haptens…
SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis
Featured Paper of the Month – January 2015
Published in Molecular Biology of the Cell by Henderson, Mark J; Wires, Emily S; Trychta, Kathleen A; Richie, Christopher T; Harvey, Brandon K
Endoplasmic reticulum (ER) calcium homeostasis is disrupted in diverse pathologies, including neurodegeneration, cardiovascular diseases, and diabetes. Temporally defining calcium dysregulation during disease progression, however, has been challenging…
A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons
Hot Off the Press! – November 2014
Qi, Jia; Zhang, Shiliang; Wang, Hui-Ling; Wang, Huikun; de Buendia, Jose Jesus Aceves; Hoffman, Alexander F; Lupica, Carl R; Seal, Rebecca P; Morales, Marisela
Nat Commun, 5 , pp. 5390, 2014, ISSN: 2041-1723 (Electronic); 2041-1723 (Linking).
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Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice.
Hot Off the Press! – November 2014
Zhang, Hai-Ying; Gao, Ming; Liu, Qing-Rong; Bi, Guo-Hua; Li, Xia; Yang, Hong-Ju; Gardner, Eliot L; Wu, Jie; Xi, Zheng-Xiong
Proc Natl Acad Sci U S A, 111 (46), pp. E5007-15, 2014, ISSN: 1091-6490 (Electronic); 0027-8424 (Linking).
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Serotonergic versus Nonserotonergic Dorsal Raphe Projection Neurons: Differential Participation in Reward Circuitry
Hot Off the Press! – September 2014
McDevitt, Ross A; Tiran-Cappello, Alix; Shen, Hui; Balderas, Israela; Britt, Jonathan P; Marino, Rosa A M; Chung, Stephanie L; Richie, Christopher T; Harvey, Brandon K; Bonci, Antonello
Cell Reports, 8 (6), pp. 1857–1869, 2014, ISBN: 2211-1247.
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Single rodent mesohabenular axons release glutamate and GABA
Hot Off the Press! – September 2014
Root, David H; Mejias-Aponte, Carlos A; Zhang, Shiliang; Wang, Hui-Ling; Hoffman, Alexander F; Lupica, Carl R; Morales, Marisela
Nat Neurosci, 17 (11), pp. 1543–1551, 2014, ISSN: 1546-1726 (Electronic); 1097-6256 (Linking).
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