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Advances in the science and treatment of alcohol use disorder.

A graphical abstract from this studyReviews To Read – March 2020.

In this review, the authors critically report the scientific and clinical evidence supporting alcohol use disorder as a treatable disease using medications and/or behavioral treatments. Approved treatments and promising new interventions are reviewed and discussed, with a special emphasis on personal treatment approaches. The authors also note the critical importance of increasing education and training of health care providers on addiction medicine to enhance the implementation of effective treatments in clinical practice.

Witkiewitz, K; Litten, R Z; Leggio, L

Advances in the science and treatment of alcohol use disorder. Journal Article

In: Sci Adv, vol. 5, no. 9, pp. eaax4043, 2019, ISSN: 2375-2548 (Electronic); 2375-2548 (Linking).

Abstract | Links

@article{Witkiewitz:2019fk,
title = {Advances in the science and treatment of alcohol use disorder.},
author = {K Witkiewitz and R Z Litten and L Leggio},
url = {https://www.ncbi.nlm.nih.gov/pubmed/31579824},
doi = {10.1126/sciadv.aax4043},
issn = {2375-2548 (Electronic); 2375-2548 (Linking)},
year = {2019},
date = {2019-09-25},
journal = {Sci Adv},
volume = {5},
number = {9},
pages = {eaax4043},
address = {Department of Psychology and Center on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, 2650 Yale Blvd. SE, Albuquerque, NM 87106, USA.},
abstract = {Alcohol is a major contributor to global disease and a leading cause of preventable death, causing approximately 88,000 deaths annually in the United States alone. Alcohol use disorder is one of the most common psychiatric disorders, with nearly one-third of U.S. adults experiencing alcohol use disorder at some point during their lives. Alcohol use disorder also has economic consequences, costing the United States at least $249 billion annually. Current pharmaceutical and behavioral treatments may assist patients in reducing alcohol use or facilitating alcohol abstinence. Although recent research has expanded understanding of alcohol use disorder, more research is needed to identify the neurobiological, genetic and epigenetic, psychological, social, and environmental factors most critical in the etiology and treatment of this disease. Implementation of this knowledge in clinical practice and training of health care providers is also needed to ensure appropriate diagnosis and treatment of individuals suffering from alcohol use disorder.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

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Alcohol is a major contributor to global disease and a leading cause of preventable death, causing approximately 88,000 deaths annually in the United States alone. Alcohol use disorder is one of the most common psychiatric disorders, with nearly one-third of U.S. adults experiencing alcohol use disorder at some point during their lives. Alcohol use disorder also has economic consequences, costing the United States at least $249 billion annually. Current pharmaceutical and behavioral treatments may assist patients in reducing alcohol use or facilitating alcohol abstinence. Although recent research has expanded understanding of alcohol use disorder, more research is needed to identify the neurobiological, genetic and epigenetic, psychological, social, and environmental factors most critical in the etiology and treatment of this disease. Implementation of this knowledge in clinical practice and training of health care providers is also needed to ensure appropriate diagnosis and treatment of individuals suffering from alcohol use disorder.

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  • https://www.ncbi.nlm.nih.gov/pubmed/31579824
  • doi:10.1126/sciadv.aax4043

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