National Institute on Drug Abuse Intramural Research Program

Position

Former Special Volunteer, Integrative Neurobiology Section

Contact

Triad Technology Center
333 Cassell Drive
Room 4500
Baltimore, MD 21224

Education

Ph.D. Student - Pharmacology - Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional – CINVESTAV, México.

M.S. – Pharmacology - Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional – CINVESTAV, México (2014)

B.S. - Pharmacobiological Chemist - Universidad Michoacana de San Nicolas de Hidalgo – UMSNH, México (2008).

Research Interests

Baruc received his B.S. from the Universidad Michoacán de San Nicolas de Hidalgo in 2008, where he studied the effect of solvents (common abuse drug in Mexico City) on umami-taste perception. He received his M.S. from the Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional in 2014, where he was involved in research related to the dopaminergic system and motor disorders, specifically ADHD and Parkinson’s disease. Currently, as part of his doctoral degree, he is studying the modulation of the D3-nf isoform over the D1R-D3R heterodimer in Parkinson’s disease conditions.

Selected Publications

2009

Gauthereau-Torres, Marcia Yvette; Martinez-Revollar, Gabriela; Plancarte-Miranda, Martha; Giron-Abarca, Lizbeth; Campos-Campos, Baruc; Mercado-Camargo, Rosalio

Effects of chronic solvent abuse exposure on umami taste perception. Journal Article

In: Proc West Pharmacol Soc, vol. 52, pp. 99–103, 2009, ISSN: 0083-8969 (Print); 0083-8969 (Linking).

Abstract | Links

@article{Gauthereau-Torres:2009aa,

title = {Effects of chronic solvent abuse exposure on umami taste perception.},

author = {Marcia Yvette Gauthereau-Torres and Gabriela Martinez-Revollar and Martha Plancarte-Miranda and Lizbeth Giron-Abarca and Baruc Campos-Campos and Rosalio Mercado-Camargo},

url = {https://www.ncbi.nlm.nih.gov/pubmed/22128434},

issn = {0083-8969 (Print); 0083-8969 (Linking)},

year  = {2009},

date = {2009-01-01},

journal = {Proc West Pharmacol Soc},

volume = {52},

pages = {99--103},

address = {Facultad de Quimico Farmacobiologia, Universidad Michoacana de San Nicolas de Hidalgo, Michoacan, Mexico. mgtorres@umich.mx},

abstract = {Inhalant abuse constitutes an important public health problem in Mexico that is more prevalent among children and adolescents. Commercial products that are abused are complex mixtures of solvents containing mainly toluene, in association with other solvents like benzene and xylene. Epidemiological evidence indicates that chronic solvent abuse exposure can cause loss of appetite among other unwanted effects. The mechanisms by which loss of appetite is produced are unknown. It is a matter of interest to determine if loss of appetite is related to changes in taste perception. One of the basic flavors detected by the taste system is umami taste (monosodium glutamate) and it has been proposed that glutamatergic receptors can play an important role in umami taste transduction and perception. It is unknown however, if chronic solvent abuse exposure can induce alterations in umami taste perception. The purpose of this work was to determine if chronic solvent exposure in rats causes alterations in glutamate solution consumption. Rats were exposed to solvents (6000 ppm) in a static chamber for 2 months, as follows: a toluene group, a benzene group, a xylene group and a control group. During the treatment, glutamate solution (120 mM) consumption, food intake and rat weights were measured. The results show that glutamate solution intake was increased in rats chronically exposed to solvents, with differences in consumption patterns between solvents. In addition, chronically exposed animals had a lower weight increase compared with unexposed rats. These data suggest that solvent inhalation originates feeding behavior alteration in rats.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}